By Steven M. Dinh and Puchun Liu (Eds.)

ISBN-10: 0841219508

ISBN-13: 9780841219502

ISBN-10: 084123809X

ISBN-13: 9780841238091

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D . & Rondeau, E . Lab Invest 1994, 71,828-37. 54. Ruoslahti, E . & Yamaguchi, Y. Cell 1991, 64,867-9. 55. Klagsbrun, M. & Baird, A . Cell 1991, 67,229-31. 56. Burgess, W. H. & Maciag, T. Annu Rev Biochem 1989, 58,575-606. 57. Moscatelli, D . J Biol Chem 1992, 267,25803-9. 58. Nugent, M. A . & Edelman, E . R. Biochemistry 1992, 31,8876-83. 59. Reilly, C. , Fritze, L. M. & Rosenberg, R. D . J Cell Physiol 1986, 129,119. 60. Benitz, W. E . , Lessler, D . , Coulson, J. D . & Bernfield, M . J Cell Physiol 1986, 127,1-7.

Karnovsky, M. J. Circ Res 1980, 46,625-34. 37. Castellot, J. , Addonizio, M. , Rosenberg, R. & Karnovsky, M. J. J Cell Biol 1981, 90,372-9. ; ACS Symposium Series; American Chemical Society: Washington, DC, 2003. ch002 30 12. , Clowes, M. M. & Clowes, A . W . J Surg Res 1997, 70,178-86. 13. Yokokawa, K . , Tahara, H . , Mandal, A . K . , Yanagisawa, M. & Takeda, T. J Clin Invest 1993, 92,2080-5. 14. Upchurch, G. , Welch, G . , Freedman, J. E . , Fabian, A . , Scribner, A . , Alpert, C. , Keaney, J.

Douglas and coworkers have demonstrated that this stimulation is blocked when the interferon -γ is mixed with Heparin (44,45). There is also evidence Heparin may directly effect the adhesion and diapedesis of leukocytes at sites of inflammation. The selectins are a group of glycoproteins which may be responsible for the initial adhesion of leukocytes to sites of inflammation. Significantly, Heparin has been shown to bind to both the P- and L - selectins which may prevent their presentation on the surface of cells at the site of inflammation (46,47).

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Advances in Controlled Drug Delivery. Science, Technology, and Products by Steven M. Dinh and Puchun Liu (Eds.)


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